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Article

Liver microRNA Profile of Induced Allograft Tolerance

5 Mar 2016

Abstract excerpt

BACKGROUND: Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. In both experimental models and clinical transplantation, total lymphoid irradiation (TLI) has been shown to induce allograft tolerance. Our goal was to identify the microRNAs (miRNAs) expressed in tolerant liver allograft recipients in an experimental model of...

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PMID: 26950716
DOI: 10.1097/tp.0000000000001105

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