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Article

Identification of microRNAs involved in acute rejection and spontaneous tolerance in murine hepatic allografts

17 Oct 2014

Abstract excerpt

Graft acceptance without the need for immunosuppressive drugs is the ultimate goal of transplantation therapy. In murine liver transplantation, allografts are accepted across major histocompatibility antigen complex barriers without the use of immunosuppressive drugs and constitute a suitable model for research on immunological rejection and tolerance. MicroRNA (miRNA) has been known to be involved in the...

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PMID: 25323448
DOI: 10.1038/srep06649

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