Article
Polypeptide release factors and stop codon recognition in the apicoplast and mitochondrion of Plasmodium falciparum.
Molecular microbiology - 1 Jun 2016
Vaishya Suniti, Kumar Vikash, Gupta Ankit, Siddiqi Mohammad Imran, Habib Saman
Abstract excerpt
Correct termination of protein synthesis would be a critical step in translation of organellar open reading frames (ORFs) of the apicoplast and mitochondrion of the malaria parasite. We identify release factors (RFs) responsible for recognition of the UAA and UGA stop-codons of apicoplast ORFs and the sole UAA stop-codon that terminates translation from the three mitochondrial ORFs. A single nuclear-encoded...
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