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Article

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease.

Journal of neuropsychology - 1 Sept 2025

Whooley Emma, Koppelmans Vincent, MacDonald Hayley J, Hall Alison, Ruitenberg Marit F L

Abstract excerpt

Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD. A total of 278 de novo PD patients (ICD-free at enrollment) were selected from the...

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Source

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Identifiers

PMID: 39876036
DOI: 10.1111/jnp.12415
PMCID: PMC12301494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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