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Article

Novel targetable biomarkers in clear cell carcinoma of the breast uncovered by molecular profiling: A study of nine cases.

The breast journal - 1 Sept 2020

Skenderi Faruk, Palazzo Juan, Swensen Jeffrey, Feldman Rebecca, Contreras Elma, Florento Elena, Gatalica Zoran, Vranic Semir

Abstract excerpt

We profiled nine pure clear cell carcinomas of the breast using massively parallel DNA and RNA sequencing (NGS), in situ hybridization (ISH), and immunohistochemistry (IHC). All cases were primary mammary clear cell carcinomas that were diagnosed in female patients (mean age: 53.4 years; range: 31-69 years). Based on our findings, we conclude that the majority of clear cell carcinomas are ER/PR positive and...

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Identifiers

PMID: 32279409
DOI: 10.1111/tbj.13842
PMCID: PMC7586831

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