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Article

A targeted next-generation sequencing method for identifying clinically relevant mutation profiles in lung adenocarcinoma.

Scientific reports - 3 Mar 2016

Shao Di, Lin Yongping, Liu Jilong, Wan Liang, Liu Zu, Cheng Shaomin, Fei Lingna, Deng Rongqing, Wang Jian, Chen Xi, Liu Liping, Gu Xia, Liang Wenhua, He Ping, Wang Jun, Ye Mingzhi, He Jianxing

Abstract excerpt

Molecular profiling of lung cancer has become essential for prediction of an individual's response to targeted therapies. Next-generation sequencing (NGS) is a promising technique for routine diagnostics, but has not been sufficiently evaluated in terms of feasibility, reliability, cost and capacity with routine diagnostic formalin-fixed, paraffin-embedded (FFPE) materials. Here, we report the validation and...

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Identifiers

PMID: 26936516
DOI: 10.1038/srep22338
PMCID: PMC4776238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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