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Article

Real-world utility of next-generation sequencing for targeted gene analysis and its application to treatment in lung adenocarcinoma.

Cancer medicine - 1 May 2021

Kim Jwa Hoon, Yoon Shinkyo, Lee Dae Ho, Jang Se Jin, Chun Sung-Min, Kim Sang-We

Abstract excerpt

PURPOSE: This study investigated the clinical utility of next-generation sequencing (NGS) for detection of genetic alterations and its implications on treatment of lung adenocarcinoma in real-world practice. PATIENTS AND METHODS: Data were reviewed for 391 patients with lung adenocarcinoma who underwent NGS between March 2017 and October 2018. Formalin-fixed, paraffin-embedded archival samples were used for...

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Identifiers

PMID: 33960703
DOI: 10.1002/cam4.3874
PMCID: PMC8124124

Genes

EGFR
ALK
BRAF
CDKN2A
KRAS
MET
RET
TP53

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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