Article
The Protective Effect of HIF-1α in T Lymphocytes on Cardiac Damage in Diabetic Mice.
Annals of clinical and laboratory science - 1 Jan 2016
Lin Ye, Tang Ying, Wang Fang
Abstract excerpt
Diabetic cardiomyopathy (DCM) is associated with functional and structural pathological changes such as hypoxia and inflammation. Hypoxia-inducible factor-1α(HIF-1α) is a core transcription factor for restoring homeostasis in intracellular oxygen and has a crucial role in preventing the development of DCM. However, the effect of HIF-1α in T lymphocytes on DCM has not been reported. We established T...
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