Article
Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain.
Genome biology and evolution - 23 Mar 2016
Zhang Bin, Han Dingding, Korostelev Yuriy, Yan Zheng, Shao Ningyi, Khrameeva Ekaterina, Velichkovsky Boris M, Chen Yi-Ping Phoebe, Gelfand Mikhail S, Khaitovich Philipp
Abstract excerpt
Small nuclear and nucleolar RNAs (snRNAs and snoRNAs) are known to be functionally and evolutionarily conserved elements of transcript processing machinery. Here, we investigated the expression evolution of snRNAs and snoRNAs by measuring their abundance in the frontal cortex of humans, chimpanzees, rhesus monkeys, and mice. Although snRNA expression is largely conserved, 44% of the 185 measured snoRNA and 40% of...
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