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Article

Mutational Landscape of Aggressive Prostate Tumors in African American Men.

Cancer research - 1 Apr 2016

Lindquist Karla J, Paris Pamela L, Hoffmann Thomas J, Cardin Niall J, Kazma Rémi, Mefford Joel A, Simko Jeffrey P, Ngo Vy, Chen Yalei, Levin Albert M, Chitale Dhananjay, Helfand Brian T, Catalona William J, Rybicki Benjamin A, Witte John S

Abstract excerpt

Prostate cancer is the most frequently diagnosed and second most fatal nonskin cancer among men in the United States. African American men are two times more likely to develop and die of prostate cancer compared with men of other ancestries. Previous whole genome or exome tumor-sequencing studies of prostate cancer have primarily focused on men of European ancestry. In this study, we sequenced and characterized...

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Source

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Identifiers

PMID: 26921337
DOI: 10.1158/0008-5472.CAN-15-1787
PMCID: PMC4772140

Genes

CDC27
ERG
OAT
PTEN
TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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