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Proteomic differences in recombinant CHO cells producing two similar antibody fragments

25 Feb 2016

Abstract excerpt

Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the production of biopharmaceuticals. To overcome unfavorable features of CHO cells, a lot of effort is put into cell engineering to improve phenotype. "Omics" studies investigating elevated growth rate and specific productivities as well as extracellular stimulus have already revealed many interesting engineering targets. However,...

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PMID: 26913574
DOI: 10.1002/bit.25957

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