Xenopus as a model organism for birth defects-Congenital heart disease and heterotaxy.

Abstract excerpt

Congenital heart disease is the leading cause of birth defects, affecting 9 out of 1000 newborns each year. A particularly severe form of congenital heart disease is heterotaxy, a disorder of left-right development. Despite aggressive surgical management, patients with heterotaxy have poor survival rates and severe morbidity due to their complex congenital heart disease. Recent genetic analysis of affected...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Body Patterning
• Share to Disease Models, Animal
• Share to N-Acetylgalactosaminyltransferases