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Article

The genetic landscape of cardiovascular left-right patterning defects.

Current opinion in genetics & development - 1 Aug 2022

Wells John R, Padua Maria B, Ware Stephanie M

Abstract excerpt

Heterotaxy is a disorder with complex congenital heart defects and diverse left-right (LR) patterning defects in other organ systems. Despite evidence suggesting a strong genetic component in heterotaxy, the majority of molecular causes remain unknown. Established genes often involve a ciliated, embryonic structure known as the left-right organizer (LRO). Herein, we focus on genetic discoveries in heterotaxy in...

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Identifiers

PMID: 35777348
DOI: 10.1016/j.gde.2022.101937
PMCID: PMC10698510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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