Article
Xenopus research: metamorphosed by genetics and genomics.
Trends in genetics : TIG - 1 Dec 2011
Harland Richard M, Grainger Robert M
Abstract excerpt
Research using Xenopus takes advantage of large, abundant eggs and readily manipulated embryos in addition to conserved cellular, developmental and genomic organization with mammals. Research on Xenopus has defined key principles of gene regulation and signal transduction, embryonic induction, morphogenesis and patterning as well as cell cycle regulation. Genomic and genetic advances in this system, including the...
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