Article
Recent acquisitions on the genetic basis of autoimmune disease.
Frontiers in bioscience : a journal and virtual library - 1 May 2008
Hill Natasha J, King Cecile, Flodstrom-Tullberg Malin
Abstract excerpt
In this review we will discuss recent progress from studies on the genetic basis of autoimmune disease and how this has advanced our understanding of the processes behind disease susceptibility and pathogenesis. We review the genetic associations with autoimmune and inflammatory disease discovered in the latest genome-wide association (GWA) scans, and discuss the importance of animal models both for generating...
Topics
- Animals
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Colitis
- Crohn Disease
- Diabetes Mellitus, Type 1
- Disease Models, Animal
- Genetic Predisposition to Disease
- Humans
- Inflammation
- Lupus Erythematosus, Systemic