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Article

Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo.

Developmental biology - 1 Apr 2016

Piacentino Michael L, Chung Oliver, Ramachandran Janani, Zuch Daniel T, Yu Jia, Conaway Evan A, Reyna Arlene E, Bradham Cynthia A

Abstract excerpt

Skeletal patterning in the sea urchin embryo requires coordinated signaling between the pattern-dictating ectoderm and the skeletogenic primary mesenchyme cells (PMCs); recent studies have begun to uncover the molecular basis for this process. Using an unbiased RNA-Seq-based screen, we have previously identified the TGF-ß superfamily ligand, LvBMP5-8, as a skeletal patterning gene in Lytechinus variegatus...

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Source

Identifiers

PMID: 26905309
DOI: 10.1016/j.ydbio.2016.02.015

Genes

BMP2
BMP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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