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Serotonin Transporter Function Is an Early Step in Left-Right Patterning in Chick and Frog Embryos

1 Jan 2005

Abstract excerpt

The neurotransmitter serotonin has been shown to regulate a number of embryonic patterning events in addition to its crucial role in the nervous system. Here, we examine the role of two serotonin transporters, the plasma membrane serotonin transporter (SERT) and the vesicular monoamine transporter (VMAT), in embryonic left-right asymmetry. Pharmacological or genetic inhibitors of either SERT or VMAT specifically...

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PMID: 16280633
DOI: 10.1159/000088451

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