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Article

Quantitative systems pharmacology and the personalized drug–microbiota–diet axis

10 Jun 2017

Abstract excerpt

Precision medicine is an emerging paradigm that aims at maximizing the benefits and minimizing the adverse effects of drugs. Realistic mechanistic models are needed to understand and limit heterogeneity in drug responses. While pharmacokinetic models describe in detail a drug's absorption and metabolism, they generally do not account for individual variations in response to environmental influences, in addition...

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PMID: 32984662
DOI: 10.1016/j.coisb.2017.06.001

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