Article
Innate and adaptive immunity in inflammatory bowel disease.
Autoimmunity reviews - 1 Jan 2014
Geremia Alessandra, Biancheri Paolo, Allan Philip, Corazza Gino R, Di Sabatino Antonio
Abstract excerpt
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC). The exact cause of IBD remains unknown. Available evidence suggests that an abnormal immune response against the microorganisms of the intestinal flora is responsible for the disease in genetically susceptible individuals. The adaptive immune response has classically been considered to play a major role in the pathogenesis...
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