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Article

CD36 is a co-receptor for hepatitis C virus E1 protein attachment

22 Feb 2016

Abstract excerpt

The cluster of differentiation 36 (CD36) is a membrane protein related to lipid metabolism. We show that HCV infection in vitro increased CD36 expression in either surface or soluble form. HCV attachment was facilitated through a direct interaction between CD36 and HCV E1 protein, causing enhanced entry and replication. The HCV co-receptor effect of CD36 was independent of that of SR-BI. CD36 monoclonal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26898231
DOI: 10.1038/srep21808

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