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Article

Claudin-6 and Occludin Natural Variants Found in a Patient Highly Exposed but Not Infected with Hepatitis C Virus (HCV) Do Not Confer HCV Resistance In Vitro.

PloS one - 1 Jan 2015

Fénéant Lucie, Ghosn Jade, Fouquet Baptiste, Helle François, Belouzard Sandrine, Vausselin Thibaut, Séron Karin, Delfraissy Jean-François, Dubuisson Jean, Misrahi Micheline, Cocquerel Laurence

Abstract excerpt

The clinical course of Hepatitis C Virus (HCV) infection is highly variable between infected individual hosts: up to 80% of acutely HCV infected patients develop a chronic infection while 20% clear infection spontaneously. Spontaneous clearance of HCV infection can be predicted by several factors, including symptomatic acute infection, favorable IFNL3 polymorphisms and gender. In our study, we explored the...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26561856
DOI: 10.1371/journal.pone.0142539
PMCID: PMC4643007

Genes

CLDN6
OCLN
IFNL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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