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Regulated Entry of Hepatitis C Virus into Hepatocytes

9 May 2017

Abstract excerpt

Hepatitis C virus (HCV) is a model for the study of virus-host interaction and host cell responses to infection. Virus entry into hepatocytes is the first step in the HCV life cycle, and this process requires multiple receptors working together. The scavenger receptor class B type I (SR-BI) and claudin-1 (CLDN1), together with human cluster of differentiation (CD) 81 and occludin (OCLN), constitute the minimal...

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PMID: 28486435
DOI: 10.3390/v9050100

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