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Article

Long-chain fatty acyl-coenzyme A suppresses hepatitis C virus infection by targeting virion-bound lipoproteins.

Antiviral research - 1 May 2020

Li Xinlei, Li Jinqian, Feng Yetong, Cai Hua, Li Yi-Ping, Peng Tao

Abstract excerpt

Hepatitis C virus (HCV) is a leading cause of chronic hepatitis and end-stage liver diseases. Mature HCV virions are bound by host-derived lipoproteins. Lack of an HCV vaccine warrants a major role of antiviral treatment in the global elimination of hepatitis C. Although direct-acting antivirals (DAAs) are replacing the interferon-based treatment and have dramatically improved the cure rate, the presence of viral...

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PMID: 32057770
DOI: 10.1016/j.antiviral.2020.104734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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