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Article

A pilot integrative genomics study of GABA and glutamate neurotransmitter systems in suicide, suicidal behavior, and major depressive disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2016

Yin Honglei, Pantazatos Spiro P, Galfalvy Hanga, Huang Yung-Yu, Rosoklija Gorazd B, Dwork Andrew J, Burke Ainsley, Arango Victoria, Oquendo Maria A, Mann John J

Abstract excerpt

Gamma-amino butyric acid (GABA) and glutamate are the major inhibitory and excitatory neurotransmitters in the mammalian central nervous system, respectively, and have been associated with suicidal behavior and major depressive disorder (MDD). We examined the relationship between genotype, brain transcriptome, and MDD/suicide for 24 genes involved in GABAergic and glutamatergic signaling. In part 1 of the study,...

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Source

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Identifiers

PMID: 26892569
DOI: 10.1002/ajmg.b.32423
PMCID: PMC4851346

Genes

GABRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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