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Article

Targeted sequencing of the LRRTM gene family in suicide attempters with bipolar disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2020

Reichman Rachel D, Gaynor Sophia C, Monson Eric T, Gaine Marie E, Parsons Meredith G, Zandi Peter P, Potash James B, Willour Virginia L

Abstract excerpt

Glutamatergic signaling is the primary excitatory neurotransmission pathway in the brain, and its relationship to neuropsychiatric disorders is of considerable interest. Our previous attempted suicide genome-wide association study, and numerous studies investigating gene expression, genetic variation, and DNA methylation have implicated aberrant glutamatergic signaling in suicide risk. The glutamatergic pathway...

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Identifiers

PMID: 31854516
DOI: 10.1002/ajmg.b.32767
PMCID: PMC8380126

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