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Article

High-Coverage Whole-Exome Sequencing Identifies Candidate Genes for Suicide in Victims with Major Depressive Disorder.

Scientific reports - 2 Aug 2017

Tombácz Dóra, Maróti Zoltán, Kalmár Tibor, Csabai Zsolt, Balázs Zsolt, Takahashi Shinichi, Palkovits Miklós, Snyder Michael, Boldogkői Zsolt

Abstract excerpt

We carried out whole-exome ultra-high throughput sequencing in brain samples of suicide victims who had suffered from major depressive disorder and control subjects who had died from other causes. This study aimed to reveal the selective accumulation of rare variants in the coding and the UTR sequences within the genes of suicide victims. We also analysed the potential effect of STR and CNV variations, as well as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28769055
DOI: 10.1038/s41598-017-06522-3
PMCID: PMC5541090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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