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GLUCOCORTICOID RECEPTOR-RELATED GENES: GENOTYPE AND BRAIN GENE EXPRESSION RELATIONSHIPS TO SUICIDE AND MAJOR DEPRESSIVE DISORDER.

Depression and anxiety - 1 Jun 2016

Yin Honglei, Galfalvy Hanga, Pantazatos Spiro P, Huang Yung-Yu, Rosoklija Gorazd B, Dwork Andrew J, Burke Ainsley, Arango Victoria, Oquendo Maria A, Mann J John

Abstract excerpt

INTRODUCTION: We tested the relationship between genotype, gene expression and suicidal behavior and major depressive disorder (MDD) in live subjects and postmortem samples for three genes, associated with the hypothalamic-pituitary-adrenal axis, suicidal behavior, and MDD; FK506-binding protein 5 (FKBP5), Spindle and kinetochore-associated protein 2 (SKA2), and Glucocorticoid Receptor (NR3C1). MATERIALS AND...

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Source

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Identifiers

PMID: 27030168
DOI: 10.1002/da.22499
PMCID: PMC4889464

Genes

SKA2
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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