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Article

Significant association between FasL gene -844T/C polymorphism and risk to hepatocellular carcinoma in Egyptian patients.

Immunology letters - 1 Apr 2016

Khalifa Rania H, Bahgat Dina M Rasheed, Darwish Hatem Abdel Hamid, Shahin Rasha Mohamad Hosny

Abstract excerpt

Fas/Fas ligand (FasL) system is the most critical apoptotic signaling entity in the extrinsic apoptotic pathway; hence mutations affecting this pathway may prevent the immune system from the removal of newly-formed tumor cells, and thus lead to tumor formation. The present study investigated the association between the FasL -844T/C polymorphism and the risk of hepatocellular carcinoma (HCC) in a cohort of...

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Identifiers

PMID: 26891954
DOI: 10.1016/j.imlet.2016.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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