Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity

18 Feb 2016

Abstract excerpt

UNLABELLED: Many viruses trigger the type I interferon (IFN) pathway upon infection, resulting in the transcription of hundreds of interferon-stimulated genes (ISGs), which define the antiviral state of the host. Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious viral disease endangering the pig industry in many countries. However, anti-CSFV ISGs are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to interferon and immune responses
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26889038
DOI: 10.1128/jvi.02718-15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase ActivityPMID 26889038Read ↗

Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling PathwaySemantic proximity Read ↗

Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1Semantic proximity Read ↗

Genetically modified pigs are protected from classical swine fever virusSemantic proximity Read ↗

FoxJ1 inhibits African swine fever virus replication and viral S273R protein decreases the expression of FoxJ1 to impair its antiviral effectSemantic proximity Read ↗

Genetically modified pigs are protected from classical swine fever virusSemantic proximity Read ↗

Npro of Classical Swine Fever Virus Suppresses Type III Interferon Production by Inhibiting IRF1 Expression and Its Nuclear Translocation.Semantic proximity Read ↗

African swine fever virus B175L inhibits the type I interferon pathway by targeting STING and 2′3′-cGAMPSemantic proximity Read ↗

Classical swine fever virus genotype 2.1 triggers stronger inflammatory and immune responses in porcine alveolar macrophages than genotype 3.4.Semantic proximity Read ↗

Swine acute diarrhea syndrome coronavirus Nsp1 suppresses IFN-λ1 production by degrading IRF1 via ubiquitin–proteasome pathwaySemantic proximity Read ↗

Two coupled mutations abolished the binding of CEBPB to the promoter of CXCL14 that displayed an antiviral effect on PRRSV by activating IFN signaling.Semantic proximity Read ↗

Antiviral Role of IFITM Proteins in Classical Swine Fever Virus InfectionSemantic proximity Read ↗

PKM2 Facilitates Classical Swine Fever Virus Replication by Enhancing NS5B Polymerase FunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.