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Antiviral Role of IFITM Proteins in Classical Swine Fever Virus Infection

30 Jan 2019

Abstract excerpt

The proteins IFITM1, IFITM2, and IFITM3 are host effectors against a broad range of RNA viruses whose roles in classical swine fever virus (CSFV) infection had not yet been reported. We investigated the effect of these proteins on CSFV replication in mammalian cells. The proteins were overexpressed and silenced using lentiviruses. Confocal microscopy was used to determine the distribution of these proteins in the...

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PMID: 30704088
DOI: 10.3390/v11020126

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