Article
Analysis of single nucleotide polymorphisms within ADAM12 and risk of knee osteoarthritis in a Chinese Han population.
BioMed research international - 1 Jan 2015
Wang Lin, Guo Lin, Tian Fengde, Hao Ruihu, Yang Tiejun
Abstract excerpt
OBJECTIVE: Osteoarthritis (OA) is a complex arthritic condition in which the genetic factor plays a major role. One of the candidate genes of is the ADAM12 gene, but no consistency has been reached till now. This study aims to investigate the potential role of four single nucleotide polymorphisms (SNPs) of the ADAM12 gene in susceptibility to knee OA and its progression in Chinese Han population. METHODS: The...
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