Article
Association between p21 Ser31Arg polymorphism and the development of cervical lesion in women infected with high risk HPV.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2016
Lima Géssica, Santos Erinaldo, Angelo Hildson, Oliveira Micheline, Heráclio Sandra, Leite Fernanda, de Melo Celso, Crovella Sergio, Maia Maria, Souza Paulo
Abstract excerpt
Infection by high-risk human papillomavirus (HR-HPV) and single nucleotide polymorphism (SNP) in genes involved in cell cycle control, as p21 and p27, are important factors in the development of different types of human cancers. This study aims at investigating whether both the p21 Ser31Arg and p27 V109G polymorphisms are associated with susceptibility to the development of cervical lesions in women HR-HPV...
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