Article
Synergic effect of oral contraceptives, GSTP1 polymorphisms, and high-risk HPV infection in development of cervical lesions.
Genetics and molecular research : GMR - 17 Aug 2017
Chagas B S, Gurgel A P A D, Paiva Júnior S S L, Lima R C P, Cordeiro M N, Moura R R, Coelho A V C, Nascimento K C G, Silva Neto J C, Crovella S, Freitas A C
Abstract excerpt
Human papillomavirus (HPV) infection is considered a risk factor for cervical cancer. Even if the high-risk HPV (HR-HPV) infection is necessary, environmental co-factors and genetic susceptibility also play an important role in cervical cancer development. In this study, a possible association of rs1695 GSTP1 polymorphisms, HR-HPV infection, and oral contraceptive use with cancer lesion development in women was...
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