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Article

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and promoter methylation in cervical oncogenic lesions and cancer.

Journal of cellular and molecular medicine - 1 Apr 2013

Botezatu Anca, Socolov Demetra, Iancu Iulia V, Huica Irina, Plesa Adriana, Ungureanu Carmen, Anton Gabriela

Abstract excerpt

The aim of this study was to investigate the role of methylenetetrahydrofolate reductase (MTHFR) polymorphisms and MTHFR methylation pattern in cervical lesions development among women from Romania, a country with high prevalence of human papillomavirus (HPV) cervical infections. To achieve this goal, blood samples and cervical cytology specimens (n = 77)/tumour tissue specimens (n = 23) were investigated. As...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Genetic Association Studies

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Papillomavirus Infections

Share to Promoter Regions, Genetic

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23444906
DOI: 10.1111/jcmm.12032
PMCID: PMC3822654

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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