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Article

The Tocotrienol-Rich Fraction Is Superior to Tocopherol in Promoting Myogenic Differentiation in the Prevention of Replicative Senescence of Myoblasts.

PloS one - 1 Jan 2016

Khor Shy Cian, Razak Azraul Mumtazah, Wan Ngah Wan Zurinah, Mohd Yusof Yasmin Anum, Abdul Karim Norwahidah, Makpol Suzana

Abstract excerpt

Aging results in a loss of muscle mass and strength. Myoblasts play an important role in maintaining muscle mass through regenerative processes, which are impaired during aging. Vitamin E potentially ameliorates age-related phenotypes. Hence, this study aimed to determine the effects of the tocotrienol-rich fraction (TRF) and α-tocopherol (ATF) in protecting myoblasts from replicative senescence and promoting...

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Identifiers

PMID: 26885980
DOI: 10.1371/journal.pone.0149265
PMCID: PMC4757569

Genes

MYOD1
MYOG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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