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Article

Murine Myoblasts Exposed to SYUIQ-5 Acquire Senescence Phenotype and Differentiate into Sarcopenic-Like Myotubes, an In Vitro Study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Apr 2024

Gerosa Laura, Malvandi Amir Mohammad, Gomarasca Marta, Verdelli Chiara, Sansoni Veronica, Faraldi Martina, Ziemann Ewa, Olivieri Fabiola, Banfi Giuseppe, Lombardi Giovanni

Abstract excerpt

The musculoskeletal system is one of the most affected organs by aging that correlates well with an accumulation of senescent cells as for other multiple age-related pathologies. The molecular mechanisms underpinning muscle impairment because of senescent cells are still elusive. The availability of in vitro model of skeletal muscle senescence is limited and restricted to a small panel of phenotypic features of...

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Identifiers

PMID: 38267369
DOI: 10.1093/gerona/glae022
PMCID: PMC10924451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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