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Article

Rosiglitazone ameliorates senescence-like phenotypes in a cellular photoaging model.

Journal of dermatological science - 1 Mar 2015

Chen Liang, Bi Bo, Zeng Jiping, Zhou Yiqun, Yang Ping, Guo Yu, Zhu Jingjing, Yang Qingjian, Zhu Ningwen, Liu Tianyi

Abstract excerpt

BACKGROUND: Rosiglitazone (RO), a second-generation thiazolidinedione used mainly in the treatment of non-insulin-dependent diabetes mellitus, has been discovered to be a high-affinity ligand for peroxisome proliferator-activated receptor-γ (PPAR-γ). Several studies have revealed that PPAR-γ is also involved in the regulation of oxidative stress and chronic inflammation associated with aging process in vivo as...

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Identifiers

PMID: 25703056
DOI: 10.1016/j.jdermsci.2015.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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