Article
Functional annotation of rheumatoid arthritis and osteoarthritis associated genes by integrative genome-wide gene expression profiling analysis.
PloS one - 1 Jan 2014
Li Zhan-Chun, Xiao Jie, Peng Jin-Liang, Chen Jian-Wei, Ma Tao, Cheng Guang-Qi, Dong Yu-Qi, Wang Wei-Li, Liu Zu-De
Abstract excerpt
BACKGROUND: Rheumatoid arthritis (RA) and osteoarthritis (OA) are two major types of joint diseases that share multiple common symptoms. However, their pathological mechanism remains largely unknown. The aim of our study is to identify RA and OA related-genes and gain an insight into the underlying genetic basis of these diseases. METHODS: We collected 11 whole genome-wide expression profiling datasets from RA...
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