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Article

Pyruvate Improved Insulin Secretion Status in a Mitochondrial Diabetes Mellitus Patient.

The Journal of clinical endocrinology and metabolism - 1 May 2016

Inoue Takeshi, Murakami Nobuyuki, Ayabe Tadayuki, Oto Yuji, Nishino Ichizo, Goto Yu-Ichi, Koga Yasutoshi, Sakuta Ryoichi

Abstract excerpt

CONTEXT: Mitochondrial diabetes is a rare form of diabetes mellitus accounting for up to 1% of all diabetes. Pyruvate therapy has been reported to be a potential therapeutic choice for patients with mitochondrial diseases. CASE DESCRIPTION: Water-based sodium pyruvate solutions (0.5 g/kg, thrice daily) were administrated orally to a 32-year-old Japanese male with mitochondrial diabetes and myopathy caused by...

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Source

Identifiers

PMID: 26885883
DOI: 10.1210/jc.2015-4293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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