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Article

MIA PaCa-2 and PANC-1 - pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors.

Scientific reports - 17 Feb 2016

Gradiz Rui, Silva Henriqueta C, Carvalho Lina, Botelho Maria Filomena, Mota-Pinto Anabela

Abstract excerpt

Studies using cell lines should always characterize these cells to ensure that the results are not distorted by unexpected morphological or genetic changes possibly due to culture time or passage number. Thus, the aim of this study was to describe those MIA PaCa-2 and PANC-1 cell line phenotype and genotype characteristics that may play a crucial role in pancreatic cancer therapeutic assays, namely neuroendocrine...

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Topics

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Share to Biomarkers, Tumor
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cell Line, Tumor

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Share to Immunohistochemistry

Share to Polymerase Chain Reaction

Share to Receptors, Somatostatin

Source

Open in PubMed Open full text

Identifiers

PMID: 26884312
DOI: 10.1038/srep21648
PMCID: PMC4756684

Genes

MIA
SSTR2
KRAS
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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