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Article

Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line.

World journal of gastroenterology - 7 Sept 2018

Gock Michael, Mullins Christina S, Harnack Christine, Prall Friedrich, Ramer Robert, Göder Anja, Krämer Oliver H, Klar Ernst, Linnebacher Michael

Abstract excerpt

AIM: To establish cell line and patient-derived xenograft (PDX) models for neuroendocrine carcinomas (NEC) which is highly desirable for gaining insight into tumor development as well as preclinical research including biomarker testing and drug response prediction. METHODS: Cell line establishment was conducted from direct in vitro culturing of colonic NEC tissue (HROC57). A PDX could also successfully be...

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Identifiers

PMID: 30197480
DOI: 10.3748/wjg.v24.i33.3749
PMCID: PMC6127660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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