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A Biomarker-Based Characterisation of EMT and Neuroendocrine Differentiation States in Pancreatic and Small Cell Hypercalcemic Ovarian Tumor Cells and Their Modulation by Transforming Growth Factor-β and Bone Morphogenetic Protein-7

2024-07-16

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) represents an extremely aggressive type of cancer due in part to early invasion and metastasis, which in turn involves epithelial-mesenchymal transition (EMT) of the tumor cells. Prompted by the discovery that two PDAC-derived tumor cell lines of the quasi-mesenchymal subtype (PANC-1, MIA PaCa-2) exhibit neuroendocrine differentiation (NED), we asked whether NED is associate...

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Literature Corpus work
e641789b-89bd-5897-86d3-7ff558dfb783
DOI
10.20944/preprints202407.1176.v1
Open publication

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A Biomarker-Based Characterisation of EMT and Neuroendocrine Differentiation States in Pancreatic and Small Cell Hypercalcemic Ovarian Tumor Cells and Their Modulation by Transforming Growth Factor-β and Bone Morphogenetic Protein-7DOI 10.20944/preprints202407.1176.v1
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