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Article

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection

17 Feb 2016

Abstract excerpt

Immunity to many human and murine gastrointestinal helminth parasites requires interleukin-4 (IL-4)-directed type 2 helper (T H 2) differentiation of CD4 + T cells to elicit type-2 immunity. Despite a good understanding of the inflammatory cascade elicited following helminth infection, the initial source of IL-4 is unclear. Previous studies using the rat helminth parasite Nippostronglyus brasiliensis , identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26883724
DOI: 10.1038/mi.2016.4

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