Nippostrongylus brasiliensis and Heligmosomoides polygyrus activate different immunomodulatory pathways in murine macrophages in vitro

Abstract excerpt

<title>Abstract</title> <p> Hookworm infections affect hundreds of millions of people worldwide and rank among the most significant neglected tropical diseases in terms of morbidity. Due to the inverse correlation between hookworm infection and the incidence of immune-mediated inflammatory diseases, considerable research has focused on understanding how parasitic helminths modulate host inflammation. <italic>He...

Topics

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• Eosinophilic Esophagitis
• IL-33, ST2, and ILC Pathways
• Immune Evasion
• Interleukin-10
• Interleukin-12
• Parasites and Host Interactions
• Research on Leishmaniasis Studies
• T-Lymphocytes, Regulatory

Identifiers and source

Literature Corpus work

1ae12519-f7fc-5ff8-9599-ae9679c6d39d

DOI

10.21203/rs.3.rs-8017434/v1