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Article

Thrombopoietin receptor is required for the oncogenic function of CALR mutants

17 Feb 2016

Abstract excerpt

Myeloproliferative neoplasms (MPNs) are diseases characterized by the pathologic expansion of myeloid cells of the hematopoietic lineage. The three ‘classical’ MPNs include polycythemia vera (PV, increase in erythrocytes), essential thrombocythemia (ET, increase in platelets) and primary myelofibrosis (PMF, usually elevated platelet counts associated with fibrotic deposition in the bone marrow). 1 MPNs are...

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PMID: 26883579
DOI: 10.1038/leu.2016.32

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Thrombopoietin receptor is required for the oncogenic function of CALR mutantsPMID 26883579Read ↗

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