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Article

Exploiting dominant-negative toxins to combat Staphylococcus aureus pathogenesis.

EMBO reports - 1 Mar 2016

Reyes-Robles Tamara, Lubkin Ashira, Alonzo Francis, Lacy D Borden, Torres Victor J

Abstract excerpt

Staphylococcus aureus (S. aureus) is a human pathogen that relies on the subversion of host phagocytes to support its pathogenic lifestyle. S. aureus strains can produce up to five beta-barrel, bi-component, pore-forming leukocidins that target and kill host phagocytes. Thus, preventing immune cell killing by these toxins is likely to boost host immunity. Here, we describe the identification of glycine-rich...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26882549
DOI: 10.15252/embr.201540994
PMCID: PMC4772982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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