Article
Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics
16 Jul 2010
Abstract excerpt
Staphylococcus aureus is a prominent human pathogen and leading cause of bacterial infection in hospitals and the community. Community-associated methicillin-resistant S. aureus (CA-MRSA) strains such as USA300 are highly virulent and, unlike hospital strains, often cause disease in otherwise healthy individuals. The enhanced virulence of CA-MRSA is based in part on increased ability to produce high levels of...
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