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Bacterial Survival Amidst an Immune Onslaught: The Contribution of the Staphylococcus aureus Leukotoxins

21 Feb 2013

Abstract excerpt

The success of Staphylococcus aureus as a human pathogen is influenced by its ability to elaborate factors that prevent infection resolution by the host immune system.Such immune-altering factors include complement inhibitory molecules, antibody binding proteins, super-antigens, as well as potent cytolytic peptides and pore-forming toxins.Here, we discuss one class of immune cell-targeting toxins, the...

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PMID: 23436994
DOI: 10.1371/journal.ppat.1003143

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