Article
Exploring Subclinical Phenotypic Features in Twin Pairs Discordant for Cleft Lip and Palate.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2017
Leslie Elizabeth J, Carlson Jenna C, Cooper Margaret E, Christensen Kaare, Weinberg Seth M, Marazita Mary L
Abstract excerpt
OBJECTIVE: Monozygotic twins of an individual with an orofacial cleft have a significantly elevated risk for orofacial cleft compared with the general population, but still the concordance rate for orofacial cleft in monozygotic twins is about 40% to 50%. The goal of this study was to determine whether unaffected cotwins have an increased frequency of orbicularis oris muscle defects, a subclinical form of...
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