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Article

Risk of oral clefts in twins.

Epidemiology (Cambridge, Mass.) - 1 May 2011

Grosen Dorthe, Bille Camilla, Petersen Inge, Skytthe Axel, Hjelmborg Jacob von Bornemann, Pedersen Jacob Krabbe, Murray Jeffrey Clark, Christensen Kaare

Abstract excerpt

BACKGROUND: Small studies have indicated that twinning increases the risk of oral cleft. METHODS: We used data from a Danish national population-based cohort study to investigate whether twinning was associated with isolated oral cleft, and to estimate the twin probandwise concordance rate and heritability. Twins (207 affected/130,710) and singletons (7766 affected/4,798,526) born from 1936 through 2004 in...

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Identifiers

PMID: 21423016
DOI: 10.1097/EDE.0b013e3182125f9c
PMCID: PMC3089024

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Source receipt: pubmed, retrieved 7 Sept 2026.

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